C0lc00517g 1679..1687
نویسندگان
چکیده
The recent shift among developers of microfluidic technologies toward modularized ‘‘plug and play’’ construction reflects the steadily increasing realization that, for many would-be users of microfluidic tools, traditional clean-room microfabrication is prohibitively complex and/or expensive. In this work, we present an advanced modular microfluidic construction scheme in which pre-fabricated microfluidic assembly blocks (MABs) can be quickly fashioned, without expertise or specialized facilities, into sophisticated microfluidic devices for a wide range of applications. Specifically, we describe three major advances to the MAB concept: (1) rapid production and extraction of MABs using flexible casting trays, (2) use of pre-coated substrates for simultaneous assembly and bonding, and (3) modification of block design to include automatic alignment and sealing structures. Finally, several exemplary applications of these MABs are demonstrated in chemical gradient synthesis, droplet generation, and total internal reflection fluorescence microscopy.
منابع مشابه
1679 Effect of Lovastatin on Early Carotid Atherosclerosis and Cardiovascular Events
Background HMG CoA reductase inhibitors (or statins), a new class of lipid-lowering compounds, have raised expectations for more widespread use than that of the older lipidlowering drugs. Not only are they more effective in lowering LDL cholesterol, but they are better tolerated as well. No data exist concerning the effect of statins on early carotid atherosclerosis and clinical events in men a...
متن کاملSir Hans Sloane (1660–1735): his life and legacy
Sir Hans Sloane was born in Killyleagh, Co Down, the seventh and last son of Alexander Sloane. His father, who was of Scottish ancestry, had a long association with James Hamilton, Earl of Clanbrassil who had acquired the castle in Killyleagh and extensive estates in east Down. The Hamilton family took an interest in the education of the Sloane children, and much of the early tuition of Hans wa...
متن کاملA tight bound on the set chromatic number
The purpose of this note is to provide a tight bound on the set chromatic number of a graph in terms of its chromatic number. Namely, for all graphs G, we show that χs(G) > dlog2 χ(G)e+ 1, where χs(G) and χ(G) are the set chromatic number and the chromatic number of G, respectively. This answers in the affirmative a conjecture of Gera, Okamoto, Rasmussen and Zhang.
متن کامل